聚羟基脂肪酸酯的合成和应用研究进展RESEARCH ADVANCE IN SYNTHESIS AND APPLICATION OF POLYHYDROXYALKANOATES
朱博超,焦宁宁
摘要(Abstract):
介绍了聚羟基脂肪酸酯 (PHA )的合成方法 ,重点讨论了微生物合成法、碳源、化学合成、分离方法及降低PHA生产成本的方法 ,介绍了PHA的性能及其改性研究 ,论述了PHA在生物医学、农业、电子、食品包装等领域的应用
关键词(KeyWords): 聚羟基脂肪酸酯;合成;应用;述评
基金项目(Foundation):
作者(Author): 朱博超,焦宁宁
参考文献(References):
- 1 CanettiM ,QrsoM ,SadoccoP ,etal.Influenceofthemorphologyandthesupmolecularstructureontheenzymaticdegradationofbac terialpoly(3 hydroxybutyrate).Polymer,1999,40:2587
- 2 LeeSY .Bacterialpolyhydroxyalkanoates.BiotechnologyandBio engineering,1996,49:1
- 3 HolmesPA .3Hydroxybutyratepolymers.USP ,4477654.1984
- 4 PeoplesOP .Methodforprodueingnovelpolyesterbiopolymes.USP ,5229279.1993
- 5 PeoplesOP .Methodforproducingnovelpolyesterbiopolymers.USP ,5245023.1993
- 6 HolmesPA .Separationprocess.USP ,4910145.1990
- 7 WalkerJ .Extractionofpolyβ hydroxybutyricacid.USP ,4358583.1982
- 8 StagemanJF .Extractionprocess.USP ,4562245.1985
- 9 沈忠耀,尹进,李红旗.从微生物细胞中分离提取PHB的方法综述.化工时刊,1997,11(5):40
- 10 LeeSY .Bacterialpolyhydroxyalkanoates.BiotechnologyandBio engineering,1996,49:11
- 11 LiddellJM .Productionofpolymersofhydroxyalkanoicacids.WO ,96/6178.1996
- 12 PageWJ .Mutantstrainsofazotobactervinelandiiusedforthehy perproductionof polyβ hydroxybutyrateduringexponentialgrowth.USP ,5059536.1991
- 13 PageWJ .Formationofpoly(hydroxybutyrate co hydroxyvalerte)byazotobactervinelandii.ApplEnvironMicrobiol,1992,58(9):2866
- 14 NaylorLA .ProcessforthemicrobiologicalproductionofPHA polymer.WO ,96/25509.1996
- 15 BourqueD .Productionofpolyβ hydroxybutyratefrommethanol:characterizationofanewisolateofmethylobacteriumextorquens.ApplMicrobiolBiotechnol,1992,37(1):7
- 16 UedaS .Synthesisofpoly(3 hydroxybutyrate co3 hydroxyvaler ate)frommethanolandn amylalcoholbythemethylotrophicbac teriaparacoccusdenitrificansandmethylbacteriumextorquens.Ap plEnvironMicrobiol,1992,58(11):3574
- 17 UniversityofGranada.Polyhydroxyalkanoateproduction.ES2061405.1995
- 18 DemisDE .Productionofpolyβ hydroxybutyrateintransformedescherichia.USP ,5334520.1994
- 19 YamaneT .Processforpreparationofcopolymer.USP ,5200332.1992
- 20 PoirierY .Polyhydroxybutyrate,abiodegradablethermoplastic,producedintransgenicplants.Science,1992,256:520
- 21 PoirierY .Progresstowardbiologically producedbiodegradablethermoplastics.AdvMater,1993,5(1):30
- 22 陈国强,吴琼.生物可降解塑料-聚羟基脂肪酸酯(PHA)的生产技术研究.精细与专用化学品,2001,(18):22
- 23 FriedrichS .Polyhydroxyalkanoatesynthesisinplants.USP ,6103956.2000
- 24 RenQ ,SierroN ,KellerhalsM ,etal.Propertiesofengineeringpoly(3 hydroxyalkanoates) producedinrecombinantesherichinacolistrains.JApplandEnvironMicrobio,2000,4:1311
- 25 NodaI .Biodegradablecopolymersand plasticarticlescomprisingbiodegradablecopolymersof3 hydroxyhexanoate.USP ,5536564.1996
- 26 HubbsJC .Processfortheproductionofpoly(3 hydroxylka noates).USP ,5552515.1996
- 27 GassnerF ,OwenAJ .Somepropertiesofpoly(3 hydroxybu tyrate) poly(3 hydroxyvalerate)blends.PolymerInternational,1996,39:215
- 28 SaitoM ,InoueY ,YoshieN .Cocrystallizationandphasesegrega tionofblendsofpoly(3 hydroxybutyrate)andpoly(3 hydroxybu tyrate co3 hydroxyvalerate).Polymer,2001,42:5573
- 29 ChoiHJ .Viscoelasticityofbiodegradablepolymerblendsofpoly(3 hydroxybutyrate)andpoly(ethyleneoxide).Polymer,2001,42:5737
- 30 邢佩祥,安玉贤,陈成等.聚β-羟基丁酸酯或其共聚物的共混物研究进展.材料研究学报,1999,13(5):449
- 31 郭创奇,杨青芳.聚(3—羟基丁酸酯)的共混改性.化学与粘合,2002,(2):75
- 32 任耀彬,郑裕东,钟青华.聚羟基烷基酸酯及其改性研究.塑料,2001,30(5):30