谢飞;王庭慰;肖晓阳;

• 1:南京工业大学材料与工程学院

摘要(Abstract)：

简要综述了用膜乳化法制备高分子微球的机理、过程参数及其应用方面的最新进展。着重介绍了膜参数、连续相流速、膜跨压差、乳化剂及温度粘度对乳化过程的影响。

关键词(KeyWords)： 膜乳化;高分子微球;过程参数;应用;述评

Abstract:

Keywords:

基金项目(Foundation):

作者(Authors): 谢飞;王庭慰;肖晓阳;

参考文献(References)：

• 1马光辉,苏志国.高分子微球材料.北京:化学工业出版社,2005.1
• 2 Nakashima T,Shimizu M,Kukizaki M.Membrane emulsi-fication by microporous glass.Key Engineering Mater,1991,513:61~62
• 3 Simon M Joscelyne,Gun Tragardh.Membrane emulsifica-tion—a literature review.Journal of Membrane Science,2000,169(1):107~117
• 4古永红.微球的制备及其作为药物载体的研究.北京:北京化工大学,2006.1
• 5卢素敏,王洪卫,马友光.膜参数对乳化过程的影响.化学工业与工程技术,2006,27(2):32~36
• 6 Kobayashi I,Yasuno M,Iwamoto S,et al.Microscopic ob-servation of emulsion droplet formation frame apolycarbonate membrane.Colloids and Surfaces A:Physico-chemical and Engineering Aspects,2002,207(1-3):185~196
• 7 Abrahamse A J,van Lierop R,van R G M der Sman.A-nalysis of droplet formation and interactions during cross-flow membrane emulsification.Journal of MembraneScience,2002,204(1-2):125~137
• 8 Christov N C,Granchev D N,Vassileva N D,et al.Capil-lary mechanisms in membrane emulsification:Oil-in-wateremulsions stabilized by Tween 20 and milk proteins.Colloids and Surfaces A:Physicochem and Engineering As-pects,2002,209(1):83~104
• 9王志,王世昌.乳状液制备新工艺———膜乳化过程实验研究.膜科学与技术,1999,19(2):49~53
• 10 Christov N C,Ganchev D N,Vassileva N D,et al.Capil-lary mechanisms in membrane emulsification:Oil-in-wateremulsions stabilized by tween 20 and milk proteins.Colloids and Surfaces A:Physicochemical and EngineeringAspects,2002,209(1):83~104
• 11陈登飞,李娜,杨建.利用SPG膜制备O/W型乳液实验研究.膜科学与技术,2007,27(3):10~14
• 12程昌敬,褚良银,陈文梅等.微孔膜乳化过程中乳滴大小的控制.过滤与分离,2005,15(2):4~11
• 13 Krassimir D Danov,Darina K Danova,Peter A Kralchev-sky.Hydrodynamic forces acting on a microscopic emulsiondrop growing at a capillary tip in relation to the process ofmembrane emulsification.Journal of Colloid and InterfaceScience,2007,316(2):844~857
• 14 Katoh R,Asano Y,Furuya A,et al.Preparation of foodemulsions using a membrane emulsification system 2.Con-ditions for preparation of W/O food emulsions using amembrane emulsification system.Journal of JapaneseSociety of Food Science and Technology,1997,44:44~49
• 15 Omi S,Kanetaka A,Shimamori Y,et al.Magnetite mi-crocapsules prepared by glass membrane and solvent.J En-capsulation,2001,18:749~765
• 16李璐,文秀芳,皮丕辉.多孔聚合物微球的制备及其在化妆品中的应用进展.日用化学工业,2006,36(2):111~115
• 17 Ma Guanghui,Omi Shinzo,Dimonie Victoria L.Study ofthe preparation and mechanism of formation of hollow mon-odisperse polystyrene microspheres by SPG emulsificationeechnique.J Appl Polym Sci,2002,151:319~330
• 18秦璐,林海,巩方玲等.微孔膜乳化与悬浮聚合结合法制备均一PST/DVB多孔微球.过程工程学报,2007,7(3):526~530
• 19 Liu Rong,Ma Guanghui,Wan Yinhua,et al.Influence ofprocess parameters on the size distribution of PLA micro-capsules prepared by combining membrane emulsificationtechnique and double emulsion-solvent evaporationmethod.Colloids and Surfaces B:Biointerfaces,2005,45(3-4):144~153
• 20 Ma Guanghui,Nagai Masatoshi,Omi Shinzo.Effect oflauryl alcohol on morphology of uniform polystyrene?po-ly(methyl methacrylate)composite microspheres preparedby porous glass membrane emulsification technique.Jour-nal of Colloid and Interface Science,1999,219(1):110~128
• 21 Ha Youngkil,Lee Haejoon,Kim Junghuy.Large andmonodispersed polymeric microspheres with highbutadiene rubber content via membrane emulsification.Colloids and Surfaces A:Physicochemical and EngineeringAspects,1998,145(1-3):281~284
• 22 Ma Guanghui,Sone hirotaka,Omi shinzo.Preparation ofuniform-sized polystyrene-polyacrylamide composite micro-spheres from a W/O/W emulsion by membrane emulsifica-tion technique and subsequent suspension polymerization.Macromolecules,2004,37:2 954~2 964